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Sugar - Microbiome - Endotoxin

STORY AT-A-GLANCE

How Your Microbiome Influences Your Dietary Recommendations
Analysis by Dr. Joseph Mercola April 21, 2024

Contrary to popular belief among followers, Ray Peat, Ph.D., did not advocate for high consumption of sugar. While sugar is acceptable in moderation, refined sugar,
particularly in large amounts, can be problematic due to its impact on the microbiome. There’s also a debate over the best source of carbohydrates. Fruit is traditionally favored over starch. However, starch is likely superior, provided you have a healthy gut microbiome, which most people lack

Efficient mitochondrial function is crucial as it provides the energy needed to maintain an optimal gut environment. Poor mitochondrial function can lead to an imbalance in gut microbiota, favoring pathogenic over beneficial bacteria

Akkermansia, a highly beneficial bacteria in your large intestine, plays a crucial role in maintaining gut health and should constitute about 10% of the gut microbiome. However, is absent in many individuals, likely due to inadequate mitochondrial function and resultant oxygen leakage in the gut. Widespread use of antibiotics can also disrupt the microbiome by killing both beneficial and harmful bacteria, leading to a dominance of pathogenic bacteria which produce harmful endotoxins

Collagen supports skin health, joint strength, and gut health due to its amino acid profile. Collagen should ideally comprise about 5% of your daily calorie intake. Avoid going above 10% as it can be problematic

Investigators using a pro-metabolic (energy-enhancing) approach are currently experimenting with vitamins and an aspirin analog to target cancer metabolism by
inducing apoptosis through lowering intracellular pH. Preliminary studies show promising results in stopping tumor growth and even regressing tumors