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• Erstellungsdatum 18. Juli 2023
• Zuletzt aktualisiert 18. Juli 2023

Existence of Circulating Mitochondria in Human and Animal Peripheral Blood

Abstract

Mitochondria are usually located in the cytoplasm of cells where they generate adenosine triphosphate (ATP) to empower cellular functions. However, we found circulating mitochondria in human and animal blood. Electron microscopy confirmed the presence of mitochondria in adult human blood plasma. Flow cytometry analyses demonstrated that circulating mitochondria from the plasma of human cord blood and adult peripheral blood displayed the immune tolerance-associated membrane molecules such as CD270 and PD-L1 (programmed cell death-ligand 1). . . .